RIRS vs. URSL vs. Mini-PCNL: How Kidney Stone Procedures Differ and How Your Urologist Chooses

A urologist in a white coat holding a medical endoscopic instrument, featuring text that reads "Prevent Another Stone: 3 Ways to Treat Kidney Stones".

When a kidney stone cannot pass on its own, there is no single “best” operation for every patient. Instead, urologists match the procedure to where the stone is sitting, how large and dense it is, and how safely the fragments can be cleared:

  • URSL (Ureteroscopic Lithotripsy) uses a thin scope passed through the natural urinary passage to break up stones stuck inside the ureter (the narrow drainage tube between the kidney and bladder).
  • RIRS (Retrograde Intrarenal Surgery) uses a bendable, flexible scope passed through the same natural urinary channel to reach further upward and laser-dust stones sitting inside the kidney’s internal chambers, typically measuring up to 20 mm (2 cm).
  • PCNL and Mini-PCNL (Percutaneous Nephrolithotomy) use a small keyhole opening (roughly 0.5 to 1 cm) in the back to reach the kidney directly, allowing the surgeon to break up and suction out large stones (over 20 mm) or complex multi-chamber stones in a single sitting.
  • ESWL (Extracorporeal Shock Wave Lithotripsy) focuses sound waves from outside the body (without scopes or lasers) to crack selected smaller, softer stones so the fragments can pass in the urine over several weeks.

Even though hospital brochures often groupseveral of these treatments under the broad label of “laser surgery” or “lithotripsy,” each approach works through a different pathway and carries its own recovery trade-offs. Understanding why a urologist recommends one method over another can help you read your scan report with less anxiety and ask the right questions during your consultation.

(If you have just been diagnosed with a small stone and are still wondering whether it might pass with fluids and medicine alone, read our earlier guide on what size kidney stone needs laser surgery.)

First, Clear Up a Common Confusion: Does “Lithotripsy” Always Mean Laser Surgery?

Patients across Tiruchirappalli often hear two different people describe “lithotripsy” in completely opposite ways. One person says they lay on a cushion while a machine tapped their back with sound waves and went home without anesthesia; another says they went into an operating theater under anesthesia while a surgeon used a laser fiber through a telescope.

Both patients are describing a form of lithotripsy—a medical word built from Greek roots that simply means “stone breaking” (Frimley Health NHS Foundation Trust). In modern urology, however, stones can be broken in two very different ways:

  1. External Shock Wave Lithotripsy (ESWL or SWL): An X-ray or ultrasound machine pinpoints the stone from outside the body, and a device called a lithotripter sends focused acoustic shock waves through the skin to crack the stone into sand-like pieces (Urology Care Foundation). No scope enters the body, and no laser is used.
  2. Internal (Intracorporeal) Laser Lithotripsy: A urologist guides a miniature camera (an endoscope) directly up to the stone—either through the natural urinary passage (URSL or RIRS) or through a tiny keyhole tract in the back (PCNL / Mini-PCNL)—and touches the stone with a hair-thin laser fiber (such as a Holmium:YAG or Thulium fiber laser) to turn it into fine powder or removable fragments (Journal of Clinical Medicine EAU/AUA Guideline Review).

Knowing which type of lithotripsy is being discussed is the first step toward making sense of your treatment plan.

Why Location Changes Everything: A Kidney Stone vs. a Ureteric Stone

Before looking at stone size, your urologist looks at where the stone is located on your ultrasound or CT scan. The urinary tract has two main upper zones, and each requires different instruments (NIDDK):

  • Inside the Kidney (Renal Pelvis and Calyces): The kidney is shaped like a central funnel (the renal pelvis) branching into smaller cup-like chambers called calyces (upper, middle, and lower poles). A stone sitting quietly in one of these chambers may not block urine right away, but reaching it from below requires a camera that can bend around sharp corners.
  • Inside the Ureter (Ureteric Stone): The ureter is the muscular tube—only about 3 to 4 millimeters wide—that carries urine down from the kidney to the bladder. When a stone drops out of the kidney and wedges inside the upper, middle, or lower ureter, it blocks urine outflow, stretches the kidney capsule, and triggers the sudden, wave-like back and groin pain known as renal colic.

Because the ureter is a relatively straight vertical tunnel while the inside of the kidney is a maze of angled chambers, the surgical tool used for a ureteric stone (URSL) is different from the tool used for a stone deep inside the kidney (RIRS or PCNL).

How the Four Main Stone Procedures Work

1. URSL (Ureteroscopic Lithotripsy) — For Stones Stuck in the Ureter

What it is: URSL (also called semi-rigid ureteroscopy or URS) is an endoscopic procedure designed specifically for stones lodged in the ureter (Urology Care Foundation).

How it works: Under spinal or general anesthesia, the urologist passes a thin, straight or semi-rigid optical telescope (ureteroscope) through the natural opening of the urethra, across the bladder, and directly into the affected ureter—making no cuts on the skin (NIDDK). Once the camera brings the stuck stone into direct view, a laser fiber is passed through the scope to break the stone into tiny fragments or fine dust, and a miniature wire basket may be used to lift out larger pieces.

When it is typically chosen:

  • Stones trapped in the lower, middle, or upper ureter that have failed to pass on their own or are too large (especially over 10 mm) to pass safely (Journal of Clinical Medicine EAU/AUA Guideline Review).
  • Ureteric stones causing persistent pain despite medication, ongoing urinary blockage, or kidney strain.

Important limitations: Because a semi-rigid ureteroscope cannot bend back on itself, it cannot safely reach stones tucked inside the angled lower chambers of the kidney. If a high ureteric stone slips upward into the kidney during URSL (a phenomenon called retropulsion), the surgeon may need to switch to a flexible scope (RIRS) or place a temporary stent and clear the stone in a planned follow-up session.

2. RIRS (Retrograde Intrarenal Surgery) — “No-Cut” Flexible Laser Surgery Inside the Kidney

What it is: RIRS is an advanced form of flexible ureteroscopy (“retrograde” means traveling backward against the normal flow of urine; “intrarenal” means inside the kidney itself).

How it works: Under general anesthesia, the surgeon passes a steerable, flexible digital or fiber-optic scope through the urethra, bladder, and ureter all the way into the internal chambers of the kidney (Urology Care Foundation). Often, a thin protective sleeve called a ureteral access sheath is placed first to let the scope slide gently in and out and keep fluid pressure inside the kidney low (Journal of Clinical Medicine EAU/AUA Guideline Review). Because the tip of an RIRS scope can bend up to 270 degrees, the urologist can steer into the upper, middle, or lower kidney poles and use a laser fiber to vaporize and “dust” the stone into microscopic powder that washes out with urine.

When it is typically chosen:

Important limitations: RIRS clears stones by turning them into dust that must drain down the narrow ureter over days or weeks. If a stone is very large (over 20 mm), dusting it takes a long operating time and leaves behind a heavy load of sand and fragments (PMC Comparative Meta-Analysis). For large stones, choosing RIRS often means accepting a higher chance of needing a second (staged) procedure to achieve complete clearance. Occasionally, a patient’s ureter is naturally too narrow (“tight ureter”) to admit the scope safely on the first day; in that situation, the safest decision is to place a temporary DJ stent for one to two weeks to let the ureter gently widen before performing RIRS.

3. PCNL and Mini-PCNL (Percutaneous Nephrolithotomy) — Keyhole Access for Large or Complex Stones

What it is: PCNL is a minimally invasive keyhole surgery performed through a small incision (typically about 0.5 to 1 cm) in the back or flank that enters the kidney’s collecting system directly (Urology Care Foundation; Newcastle NHS Foundation Trust). Mini-PCNL (miniaturized PCNL) uses narrower sheaths and slender instruments (12 to 22 French instead of standard >22 French instruments) to reduce tissue stretching and blood loss while maintaining direct access (Journal of Clinical Medicine EAU/AUA Guideline Review; Urology Care Foundation).

How it works: Under general anesthesia, the surgeon uses ultrasound or X-ray guidance to place a fine needle through the back skin directly into the kidney chamber holding the stone (Newcastle NHS Foundation Trust). A narrow working tunnel (tract) is dilated over the needle, and a rigid or miniature nephroscope is introduced. Unlike RIRS—where fragments must travel all the way down the ureter—PCNL and Mini-PCNL allow the surgeon to break the stone with laser, ultrasonic, or pneumatic energy and suction or lift the broken pieces straight out through the back tube during the operation (Urology Care Foundation).

When it is typically chosen:

Important limitations: Because PCNL creates a direct puncture through the vascular tissue of the kidney, it is not incision-free. It requires general anesthesia, typically involves a 2-to-4-day hospital stay, may leave a temporary external kidney drainage tube (nephrostomy) for 24 to 48 hours alongside an internal stent (unless an uncomplicated “tubeless” Mini-PCNL is appropriate), and carries a higher risk of bleeding than ureteroscopy (Newcastle NHS Foundation Trust; Journal of Clinical Medicine EAU/AUA Guideline Review).

4. ESWL (Extracorporeal Shock Wave Lithotripsy) — Non-Invasive External Sound Waves

What it is: ESWL is the only completely non-surgical stone-breaking treatment, delivering shock waves from an external machine through the skin (NIDDK).

When it is considered—and why it is not suitable for every stone: Under EAU and AUA guidelines, ESWL is a valid option for selected smaller, uncomplicated stones (generally under 10 mm, or 10 to 20 mm in the upper or middle kidney with favorable anatomy). However, ESWL only cracks the stone; your kidney and ureter still have to pass all the resulting gravel on their own. ESWL is much less effective—and often avoided—when:

At-a-Glance Comparison: URSL vs. RIRS vs. PCNL / Mini-PCNL vs. ESWL

Clinical FeatureURSL (Semi-Rigid Ureteroscopy)RIRS (Flexible Ureteroscopy)PCNL / Mini-PCNL (Keyhole Kidney Surgery)ESWL (External Shock Wave Lithotripsy)
Primary Stone LocationInside the ureter (lower, mid, or upper tube) (Urology Care Foundation)Inside the kidney chambers or upper ureter (Urology Care Foundation)Inside the kidney (especially large or lower-pole stones) (EAU/AUA Review)Selected kidney or upper/distal ureter stones (EAU/AUA Review)
Typical Guideline Size RangeUreteric stones failing passage or >10 mm (EAU/AUA Review)Kidney stones <20 mm (up to 2 cm) (EAU/AUA Review)Kidney stones >20 mm (>2 cm), staghorn, or complex 10–20 mm lower-pole stones (EAU/AUA Review)Uncomplicated stones <10 mm (or selected 10–20 mm soft stones) (EAU/AUA Review)
Skin Incision Required?No (enters via natural urethral passage) (NIDDK)No (enters via natural urethral passage) (NIDDK)Yes — a small keyhole cut (~0.5 to 1 cm) in the back/flank (Urology Care Foundation)No (shock waves delivered through the skin) (NIDDK)
How Stone Fragments LeaveLaser-dusted or extracted with a micro-basket; dust passes in urine (Urology Care Foundation)Laser-dusted into fine powder that washes out in urine over days/weeksBroken and suctioned or lifted directly out through the back sheath (Urology Care Foundation)Cracked into pieces that must pass naturally in urine over weeks (Urology Care Foundation)
Typical AnesthesiaSpinal or General Anesthesia (NIDDK)General Anesthesia (helps control breathing & kidney movement)General Anesthesia (Urology Care Foundation)Sedation / Analgesia or light anesthesia (NIDDK)
Usual Hospital StayDay-case or 1 overnight stay (Urology Care Foundation)Day-case or 1 overnight stay (Urology Care Foundation)Typically 2 to 4 days (shorter in selected Mini-PCNL cases) (Newcastle NHS)Outpatient / Same-day discharge (Urology Care Foundation)
Temporary Tubes / StentsInternal DJ stent often placed for 3–14 days if swelling is present (EAU/AUA Review)Internal DJ stent commonly placed for 1–4 weeksInternal DJ stent and/or temporary back drain (nephrostomy) for 24–48 hrs (Newcastle NHS)Stent rarely placed routinely unless blockage risk is high (EAU/AUA Review)

Beyond Millimeters: 5 Scan & Health Factors That Change the Surgical Plan

Patients often ask why two people who both have a “14 mm kidney stone” might be advised to have two completely different operations. Under EAU and AUA guidelines, a urologist evaluates five details on your Non-Contrast CT (NCCT) scan and blood/urine tests before recommending a procedure:

1. Stone Hardness (Hounsfield Units on CT)

An ultrasound can show a stone’s shadow, but a Non-Contrast CT KUB scan measures its physical density in Hounsfield Units (HU). Softer stones (such as pure uric acid stones, often 300–500 HU) respond differently than dense calcium oxalate monohydrate or brushite stones (often >1,000 to 1,500 HU). Guidelines note that external shock waves (ESWL) frequently fail when stone density exceeds 1,000 HU (Journal of Clinical Medicine EAU/AUA Guideline Review), whereas Holmium and Thulium lasers used during URSL, RIRS, and Mini-PCNL can fragment stones of any hardness.

2. Lower-Pole Kidney Anatomy

The bottom chamber of the kidney (the lower pole) drains upward against gravity into the ureter. If a 15 mm stone sits in a lower calyx with a long, narrow neck (infundibulum) or a steep angle, dust created during RIRS or ESWL may settle back to the bottom rather than washing out (PMC Comparative Meta-Analysis). In those anatomical cases, Mini-PCNL often provides a higher single-session stone-free rate because the fragments are evacuated directly out through the back sheath (Journal of Clinical Medicine EAU/AUA Guideline Review).

3. Why “No-Cut” RIRS Isn’t Always Better Than Keyhole Mini-PCNL for Stones Over 2 cm

It is natural to prefer an incision-free procedure like RIRS over a keyhole procedure like PCNL. However, for large stones above 20 mm (2 cm) or staghorn stones, trying to laser-dust the entire stone through a flexible scope takes prolonged operating time, increases fluid pressure inside the kidney, and often requires two or more separate surgeries to clear all the fragments (PMC Comparative Meta-Analysis). A single-session PCNL or Mini-PCNL through a 0.5–1 cm keyhole opening clears large stone volumes much faster and more completely, making it the strong first-line guideline recommendation for stones over 20 mm (Journal of Clinical Medicine EAU/AUA Guideline Review).

4. Active Urine Infection: Emergency Drainage First, Stone Removal Second

This is one of the most important safety principles in urology. If a stone blocks the ureter AND the trapped urine behind it becomes infected (causing fever, chills, or cloudy/foul-smelling urine), firing a laser or pumping irrigation fluid into the kidney during stone surgery can push bacteria into the bloodstream, triggering life-threatening urosepsis (Journal of Clinical Medicine EAU/AUA Guideline Review). In an infected, obstructed kidney, both the EAU and AUA guidelines mandate a two-stage safety pathway:

  1. Stage 1 (Urgent Decompression): Immediately place a temporary internal DJ stent or an external percutaneous nephrostomy tube to drain the infected urine and administer targeted intravenous antibiotics (Newcastle NHS Foundation Trust).
  2. Stage 2 (Definitive Stone Removal): Only after the fever and infection have completely cleared (often days or a couple of weeks later) does the urologist perform URSL, RIRS, or PCNL to remove the stone safely.

5. Blood Thinners, Solitary Kidneys, and Medical History

If you have only one functioning kidney (a solitary kidney), a transplanted kidney, or heart stents requiring uninterrupted blood thinners (anticoagulants or antiplatelets), your surgical risk profile changes (Journal of Clinical Medicine EAU/AUA Guideline Review). Because ureteroscopy (URSL/RIRS) does not puncture the kidney tissue, guidelines recommend it over PCNL or ESWL when blood thinners cannot be safely paused.

Illustrative Scenarios: How Two Patients Receive Different Recommendations

(Note: The following examples are hypothetical clinical scenarios created for patient education and do not depict real individual patients.)

  • Hypothetical Scenario A (Lower Ureteric Stone): A 38-year-old teacher has an 8 mm stone stuck in the lower ureter near the bladder, causing repeated side pain for three weeks despite prescribed medication. Because the stone is inside the lower ureter tunnel, Laser URSL allows a semi-rigid scope to reach it directly through the bladder, fragment it with a laser without any skin incision, and relieve the blockage—usually with same-day or next-day discharge.
  • Hypothetical Scenario B (Hard Mid-Kidney Stone): A 46-year-old office worker has a 13 mm stone (1,250 HU density) inside the middle chamber of the kidney. Because the stone is inside the kidney (above the ureter) and is too dense for external shock waves (ESWL), RIRS with a flexible ureteroscope allows the surgeon to steer into the kidney chamber and laser-dust the stone without a skin cut.
  • Hypothetical Scenario C (Large Lower-Pole Kidney Stone): A 55-year-old farmer has a 24 mm (2.4 cm) stone filling the lower pole of the kidney. Attempting RIRS would leave behind a large volume of gravel in a gravity-dependent pocket and likely require a second operation. Here, PCNL or Mini-PCNL through a tiny keyhole opening in the back allows the surgeon to break and suction the stone pieces directly out of the kidney in a single sitting.

Setting Realistic Expectations: Recovery, Stents, and Follow-Up

Honest surgical preparation means knowing that “minimally invasive” does not mean “zero symptoms afterward.” Regardless of which procedure you and your urologist choose, keep these four recovery realities in mind:

  1. Temporary Stent Symptoms Are Common: After URSL, RIRS, or tubeless Mini-PCNL, surgeons frequently place a temporary internal Double-J (DJ) stent to prevent ureteral swelling from blocking urine flow (Urology Care Foundation). While the stent is in place, mild burning during urination, frequent bathroom trips, pink-tinged urine after walking, and a brief pulling ache in the back when you pass urine are common and temporary. For a full day-by-day coping guide and what happens during the 3-minute removal visit, read our dedicated article on living with a DJ stent after kidney stone surgery.
  2. Dust and Small Fragments Take Time to Clear: After RIRS or ESWL, microscopic stone dust or sand-like particles pass out in your urine over several days or weeks. The EAU guidelines note that routine follow-up imaging is important to confirm clearance, and scanning too early (within the first 4 weeks) can sometimes pick up harmless passing dust. Your urologist will schedule an ultrasound, X-ray, or low-dose CT at the right interval for your case.
  3. Collecting a Stone Fragment Helps Prevent the Next Stone: Removing a stone solves today’s blockage, but it does not automatically stop new stones from forming in the future. Whenever a solid stone fragment is retrieved during PCNL, URSL, or RIRS, ask your surgical team whether it can be sent for laboratory composition testing. As explained in our guide to kidney stone analysis and recurrence prevention, knowing whether your stone is calcium oxalate, uric acid, or infection-related (struvite) allows your doctor to tailor your fluids, diet, and any needed 24-hour urine tests—rather than relying on generic internet food bans. (Note: Always check with your doctor before increasing daily fluid intake if you have heart failure, chronic kidney disease, or prescribed fluid restrictions.)

Urgent Warning Signs: When Not to Wait for a Routine Appointment

Whether you are waiting for a scheduled stone procedure or recovering at home after URSL, RIRS, or PCNL, certain symptoms require immediate emergency medical evaluation (NIDDK; EAU/AUA Guideline Review):

  • Fever of 38°C (100.4°F) or higher, shaking chills, or shivering (rigors): A fever combined with a urinary stone or recent stone procedure can signal a trapped kidney infection or urosepsis and must be treated as a medical emergency.
  • Inability to pass urine (anuria) or a sudden, sharp drop in urine output.
  • Severe, worsening flank or abdominal pain that does not settle with your prescribed pain medication.
  • Heavy, dark-red bleeding or large blood clots in the urine that make urination difficult.
  • Persistent nausea and vomiting that prevent you from keeping fluids or oral medications down.

Emergency Instruction: If you develop any of these warning signs, go directly to the nearest hospital emergency department. Never wait for an online booking form confirmation or a WhatsApp reply during a medical emergency.

6 Questions to Ask Your Urologist Before Kidney Stone Surgery

Bringing your ultrasound or CT films to your consultation—along with a list of your regular medications (especially blood thinners like aspirin or clopidogrel) and recent blood creatinine/urine culture reports—helps your urologist map out the safest plan. Consider asking:

  1. Where exactly is my stone located (kidney chamber vs. ureter), and what are its size and CT density (Hounsfield Units)?
  2. Which procedure—URSL, RIRS, Mini-PCNL/PCNL, or ESWL—do you recommend for my specific stone, and why is it safer or more effective than the alternatives?
  3. Given the size of my stone, is it realistic to expect complete clearance in a single procedure, or is there a chance we will need a staged second session?
  4. Will I likely need a temporary internal DJ stent (or, for PCNL, a short-term back drainage tube), and when and how will it be removed?
  5. Does my urine test show any sign of infection that needs treatment or drainage before we touch the stone?
  6. Will you be able to save a stone fragment during the procedure for laboratory stone analysis so we can work on preventing future stones?

Discussing Your Kidney Stone Scan and Procedure Options in Trichy

If you have been diagnosed with a kidney or ureteric stone and want to understand whether conservative monitoring, URSL, RIRS, or Mini-PCNL/PCNL is the most appropriate choice for your scan findings, a detailed urology consultation can help clarify your options.

Dr. S. Sureshbalaji (MS, DNB, MCh – Urology), Consultant Urologist & Andrologist, provides kidney stone evaluation and surgical counseling for patients across Tiruchirappalli (Trichy) as well as regional consultation clinics in Perambalur and Pudukkottai (please note that an outpatient consultation location is for clinical assessment and follow-up; surgical procedures are scheduled at appropriate hospital facilities equipped for endoscopic or percutaneous stone care).

  • Explore available procedures on our Urology Treatments page.
  • Learn more about Dr. S. Sureshbalaji’s background on the About page.
  • To request a non-emergency consultation slot at our Trichy (Palpannai / Velan Multispeciality Hospital), Perambalur, or Pudukkottai clinics, submit a request via the Online Appointment Bookings page or check clinic timings on the Contact page. (All online and WhatsApp appointment requests are subject to schedule confirmation by the clinic team.)

Medical Disclaimer: This article is provided for general educational purposes to help patients and families understand kidney stone procedures. It does not constitute a personal medical diagnosis or replace an in-person evaluation by a qualified urologist.

Frequently Asked Questions (FAQs)

1. Is RIRS always better than PCNL because it has no skin incision?

No. While RIRS avoids any skin incision by traveling through the natural urinary passage, it is generally best suited for kidney stones under 20 mm (2 cm) (EAU/AUA Guideline Review). For stones larger than 20 mm or complex staghorn stones, PCNL or Mini-PCNL (which uses a small 0.5–1 cm keyhole opening in the back) achieves a higher single-surgery clearance rate because large fragments are suctioned directly out rather than left to pass down the narrow ureter (PMC Comparative Meta-Analysis).

2. What is the difference between URSL and RIRS?

Both are endoscopic laser procedures performed through the natural urinary passage without external cuts, but they target different locations using different scopes (Urology Care Foundation). URSL uses a thin, straight or semi-rigid scope to treat stones stuck inside the ureter (the tube between the kidney and bladder). RIRS uses a longer, bendable flexible scope that can steer around corners inside the kidney’s internal chambers to laser-dust kidney stones.

3. Why did my doctor place a DJ stent instead of removing my stone right away?

There are two common clinical reasons. First, if you have a fever or urinary tract infection behind a blocking stone, immediate laser stone surgery is unsafe; guidelines require urgent drainage with a stent (or nephrostomy tube) and antibiotics first, followed by stone removal once the infection clears (EAU/AUA Guideline Review). Second, if your ureter is naturally too narrow (“tight ureter”) to pass the camera safely without tearing the delicate lining, placing a stent for 1 to 2 weeks gently dilates the ureter so RIRS or URSL can be completed safely.

4. Can uric acid kidney stones be dissolved with medicine instead of RIRS or PCNL?

In selected patients with uncomplicated pure uric acid stones (which usually appear radiolucent on standard X-rays and have low density on CT scans), oral chemolysis—using prescribed medications like potassium citrate or sodium bicarbonate to carefully alkalinize the urine—can sometimes dissolve the stone over time without surgery (EAU/AUA Guideline Review). However, this requires strict medical supervision and urine pH monitoring, does not work for calcium-based stones (the most common type), and is not appropriate when a stone is causing acute urinary obstruction or infection.

5. How soon can I return to normal work after URSL, RIRS, or Mini-PCNL?

Recovery timelines vary by individual health, job demands, and whether a temporary stent is in place. Many patients undergoing uncomplicated URSL or RIRS return home the same day or the next day and resume light desk activities within 2 to 5 days (Urology Care Foundation). Because PCNL and Mini-PCNL involve a small keyhole tract through the back muscle into the kidney, hospital stays typically last 2 to 4 days, and patients are generally advised to avoid heavy lifting or strenuous physical labor for 1 to 2 weeks while the kidney tract heals (Newcastle NHS Foundation Trust; Urology Care Foundation).

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